Creatinine Reagents – Vanguard Diagnostics

Product Overview

Creatinine Reagents are intended for the in-vitro quantitative determination of creatinine in human serum, plasma and urine using the Modified Jaffe method. The liquid reagent is supplied ready to use.

The reagent can be used with a range of clinical chemistry analysers, including Hitachi 700 series, RA 1000, RA 2000, XT, Express 550 Plus, Syncron CX4, Lisa 200, BTR 810/820/830, RA50, Erbachem-5 Plus, Ranlab 125 and Ranlab 40. Application sheets for specific semi-automatic, batch and automated analysers are available on request.

Pack size: 4 × 100 ml

For general information on creatinine testing, see MedlinePlus: Creatinine Test.

For related laboratory testing products, explore Urea UV Reagents, Glucose Reagents and Vanguard's wider Clinical Chemistry Reagents range.

Intended Use

For in vitro diagnostic use. This test is intended for the quantitative determination of creatinine in human serum, plasma and urine using the Modified Jaffe method. The assay is measured at 510 nm.

Why It Matters

Serum creatinine is a critical biomarker used to evaluate kidney function and diagnose renal disorders. According to the NHS guide on kidney function tests, elevated creatinine levels may indicate impaired kidney filtration and require further clinical investigation.

Key Features and Performance

Reagent Stability and Storage

• Store unopened vials at 2–8 °C until the expiry date on the label.

• After opening, reagents remain stable for 28 days if stored at 2–8 °C and capped properly.

• Avoid freezing and exposure to direct sunlight.

Compatible and Related Products

These reagents are validated for open-system analysers and work well with other Vanguard diagnostic products, including:

• Urea Reagents

• Glucose Reagents
  

• 3-Part & 5-Part Hematology Controls

Frequently Asked Questions (FAQs)

What method is used in this test?

The assay is based on the kinetic modified Jaffé method, in which creatinine reacts with alkaline picrate to form a coloured complex, measured photometrically.

Which sample types are accepted?

Use serum or plasma only. Avoid haemolysed or lipemic samples for best results.

Is the reagent compatible with all analysers?

Yes, it is suitable for most open-system, photometric chemistry analysers.

What is the measuring range of the assay?

Approximately 0.2 to 15 mg/dL, depending on the analyser used.

How long do the reagents remain stable after opening?

Once opened, the reagents are stable for 28 days when stored between 2–8 °C and handled according to the IFU.